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Louisville
21C Museum Hotel Louisville
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75 photos
21C Museum Hotel Louisville Exterior photo The photo shows a sunny street scene in a city, featuring a prominent golden statue of a muscular male figure, likely a depiction of the Greek god Hercules or a similar mythological character. The statue stands on a light-colored pedestal in the midd21C Museum Hotel Louisville Exterior photo This is a photograph taken inside what appears to be a restaurant or fine dining establishment. The focus is split between a dramatic piece of artwork overhead and the dining area below. **The Artwork:** Dominating the upper portion of the image is 21C Museum Hotel Louisville Exterior photo This is a photograph taken inside a well-stocked and upscale bar. In the center of the image is a smiling young woman with brown, shoulder-length hair. She is wearing a sheer, long-sleeved black top and is looking directly at the camera. The backgr

Book 21C Museum Hotel Louisville - Premium Seaview Hotel in Louisville

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From$209 /night
Check-in
14Jul
Check-out
15Jul
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

700 West Main Street, Louisville, 40202
-
Near the waterfront
Great
8.9
9.3
/10
4.6
4.5
/5

Loved by 21C Museum Hotel Louisville guests

Unique art
Stylish rooms
Excellent restaurant
Attentive staff
"I loved staying in an art museum."
Scott from United States
read full review
"The concept of hotel, excellent restuarant and gallery is amazing"
Karen from United States
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"I love the fact that this hotel doubles as a contemporary art museum."
Adrian from United States
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"A fun hotel with wall to wall unique art work."
Sal L from United States
"The hotel has an art gallery in it with some truly top notch artworks on display."
Karen B from United States
read full review

21C Museum Hotel Louisville: 21st-Century Art and Comfort in Downtown

Location

The hotel stands in downtown Louisville, close to notable attractions like the Louisville Palace and the Muhammad Ali Center. The prime location allows guests to explore the vibrant local art scene and historic landmarks within walking distance. Guests can access the Ohio River waterfront and enjoy the city's renowned culinary offerings nearby.

Art Experience

21C Museum Hotel Louisville is equal parts gallery and accommodation, showcasing contemporary art from around the world. The hotel includes rotating exhibitions and installations, providing guests with an enriching cultural experience. The dedicated museum space spans multiple floors, enhancing each guest's stay with visual art integration.

Dining

The hotel boasts proof on main, a restaurant that highlights local ingredients and Southern-inspired cuisine. Guests can enjoy a selection of craft cocktails and regional wines, enhancing their dining experience. The casual yet sophisticated atmosphere invites visitors for breakfast, lunch, and dinner.

Accommodations

Rooms feature custom-designed furniture and original artwork, offering a unique stays. The hotel has 91 distinct guest rooms, including 7 suites, each equipped with modern amenities. Every room provides a blend of luxury and creativity, ensuring a memorable lodging experience.

Business Facilities

The hotel offers 10,000 square feet of flexible meeting and event space equipped with cutting-edge technology. Business travelers have access to a dedicated business center for their needs. The unique setting of the hotel can accommodate both corporate meetings and social gatherings.

Highlights

Location: Downtown Louisville near attractions

Art Experience: Contemporary art exhibitions

Dining: Southern-inspired cuisine at proof on main

Accommodations: 91 distinct guest rooms and 7 suites

Business Facilities: 10,000 square feet of event space

“My experience at 21c Museum Hotel Louisville confirmed its status as an innovator, seamlessly blending a vibrant contemporary art museum throughout its spaces with comfortable guest rooms. The art installations, from the lobby to the hallways, offer a constantly engaging backdrop, enhanced by thoughtful touches like a complimentary bourbon nightcap, making for a stay that feels both cultured and remarkably welcoming.”
Hotel logo
James DavidEditor-in-Chief at Seaviewhotels

Select your room type

21C Museum Hotel Louisville offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
    Room Balcony
    2 persons
    29 sq. feet
    1 King-size bed
    Air conditioning
    Balcony
    room details
    Deluxe King Room
    2 persons
    31 sq. feet
    1 King-size bed
    Air conditioning
    Heating
    room details
    Corner Suite
    2 persons
    61 sq. feet
    1 King-size bed
    Air conditioning
    Bathtub
    room details
Show all rooms

Price and Room Availability Calendar

Check availability and prices for your dates now!
July 2026 - July 2027
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Check-in/ Check-out

Facilities

21C Museum Hotel Louisville offers amenities for your comfortable stay and unforgettable experiences
Facilities: Great
8.9/10Review score

General

  • No smoking on site
  • Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Luggage storage
  • Locker room
  • Allergy-free rooms
  • Lift
  • ATM/Cash machine
  • Smoke detectors
  • Electric vehicle charging station
  • Fire extinguishers

Sports & Fitness

  • Fitness centre
  • Yoga class

Guest Parking

  • Cookware/ Kitchen utensils

Services

  • Valet parking
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Welcome drink

Dining

  • Restaurant
  • Bar/ Lounge area
  • Outdoor dining area

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Cots

Spa & Leisure

  • Spa & wellness centre
  • Sauna
  • Turkish bath
  • Steam room
  • Full body massage

Room features

  • Air conditioning
  • Heating
  • Mini-bar
  • Soundproofed rooms
  • Patio
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries

Self-catering

  • Cookware/ Kitchen utensils

Media

  • Flat-screen TV

Room decor

  • Carpeted floor
Show more

Dining Onsite

At 21C Museum Hotel Louisville, dining options tantalize the senses with modern American cuisine showcased in vibrant surroundings. Guests can engage in unique culinary experiences that celebrate local flavors and spirits, all while enjoying an inviting atmosphere that is distinctly Louisville.
21C Museum Hotel Louisville Restaurant photo The photo shows a brightly colored, unique bedroom with a striking geometric ceiling. The ceiling is constructed from numerous triangular panels, each covered in a different vibrant fabric – blues, greens, reds, oranges, yellows, pinks, and purples.
21C Museum Hotel Louisville Restaurant photo The photo shows the interior of a restaurant with a whimsical and artistic decor. The walls are a mix of exposed brick and a large, colorful wallpaper depicting a vintage floral pattern. Numerous framed pictures and artwork of varying sizes and style
21C Museum Hotel Louisville Restaurant photo The photo shows a brightly lit dining area with a whimsical and eclectic decor. The walls are covered in a busy, patterned wallpaper featuring a mix of floral and figural designs in warm, muted tones. Numerous framed artworks of varying sizes and s

Proof on Main

American
Ambiance
Modern and art-infused setting, featuring eclectic decor that reflects the spirit of the city.
Key Offerings
Signature dishes crafted with a focus on local ingredients and flavors, along with special events like the Fork & Bottle dinner series showcasing guest distillers and the renowned Hog & Barrel dinner featuring Pappy Van Winkle.
Reservation
Recommended.
Hours vary.

21C Museum Hotel Louisville Location

700 West Main Street, Louisville, 40202
Explore Louisville
Local Experiences
  • Top Attractions
  • Activities
  • Dining
  • Entertainment
Kentucky Science Center
2 minutes walking
Interactive exhibits and IMAX theater showcasing science and technology. Great for families with free admission days available.
Louisville Slugger Museum & Bat Factory
3 minutes walking
Home of the iconic baseball bat. Tour the factory and see exhibits about the history of baseball in America.
Muhammad Ali Center
4 minutes walking
Museum and cultural center dedicated to the life and legacy of Muhammad Ali. Engaging exhibits on social justice and peace.
Waterfront Park
17 minutes walking
Vast park along the Ohio River featuring trails, playgrounds, and festivals. Ideal for outdoor relaxation and community events.
Discover the local attractions near 21C Museum Hotel Louisville
Check out significant attractions near 21C Museum Hotel Louisville that cater to various interests and activities.
Ideal for entertainment and nightlife: Fourth Street Live
Great for whiskey enthusiasts and distillery tours: Michter's Fort Nelson Distillery
Best for attending sporting events and concerts: KFC Yum Center
Perfect for history buffs and educational experiences: The Frazier History Museum
Kayaking on the Ohio River
5 minutes drive
Enjoy kayaking for an adventurous experience on the scenic Ohio River. Rentals available seasonally.
Spa Treatments at Soothe Spa
10 minutes drive
Relaxing spa services including massages and facials. Reservations recommended for a rejuvenating experience.
Proof On Main
1 minute walking
Farm-to-table cuisine featuring local ingredients in a contemporary setting. Ideal for special occasions.
Mussel & Burger Bar Downtown
1 minute walking
Casual spot known for gourmet burgers and mussels. Great for families, with vegetarian options available.
Bristol Bar & Grille
2 minutes walking
Charming atmosphere with Southern-inspired dishes. Excellent for casual dining with gluten-free choices.
Discover dining options near 21C Museum Hotel Louisville
Seek out a selection of dining options near 21C Museum Hotel Louisville that cater to diverse tastes and preferences.
Well suited for seafood lovers and casual dining: Atlantic No. 5
Ideal for fine dining and special occasions: Morton's The Steakhouse
Great for local cuisine and relaxed meals: Bristol Bar & Grille
Perfect for enjoying authentic Mexican flavors: Los Aztecas Mexican Restaurant
KFC Yum Center
9 minutes walking
Multi-purpose arena hosting concerts and sports events. Check schedule for family-friendly shows.
Fourth Street Live!
10 minutes walking
Vibrant entertainment district with bars, restaurants, and live music. Popular nightlife spot for all ages.
Getting around
  • City Centre
    Louisville 23 min  ·  1.2 mi
  • Airports
    Louisville (SDF) 18 min  ·  7.4 mi
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Property information and rules
Check-in
from 16:00-23:59
Check-out
until 11 am
Guest Parking
No parking available.
Internet
Wireless internet is available in the entire hotel for free.
Children & extra beds
Maximum capacity of extra beds in a room is 1. 
Pets
Pets are allowed on request.
Year renovated:
2006
Number of floors:
4
Number of rooms:
96
Former name
21c Museum Hotel

Reviews and Ratings

Feedback about 21C Museum Hotel Louisville from previous guests about their experience.
Review score
Based on 249 verified reviews
9.1 /10
Perfect
90 %
Recommend
Breakfast
2.5/10
Cleanliness
9.2/10
Comfort
9.3/10
Facilities
8.9/10
Free WiFi
10.0/10
Location
9.4/10
Paid Wi-Fi
7.5/10
Staff
8.9/10
Value for money
8.2/10
Pros
Art museum atmosphere
Helpful staff
Spacious room
Good restaurant
Good bar
Cons
Room darkness
Inattentive front desk
Careless housekeeping
Billing errors
Guest reviews
based on 1899 reviews
4.5/5
based on 184 reviews
8.9/10
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.
Open reviews
Show more reviews
FAQs
About 21C Museum Hotel Louisville
How far is 21C Museum Hotel Louisville from Louisville International Airport?
The hotel is located 10 km from Louisville International Airport.
What are some popular attractions near 21C Museum Hotel Louisville?
Nearby attractions include the Muhammad Ali Center (0.5 km), Frazier International History Museum (0.5 km), and the Louisville Slugger Museum & Factory (0.5 km).
What amenities are offered for guests at 21C Museum Hotel Louisville?
The hotel features a spa and wellness center, fitness center, sauna, and bicycle rentals.
What room amenities are provided at 21C Museum Hotel Louisville?
Rooms are equipped with free Wi-Fi, 50-inch flat-screen TVs, minibars, and iPod docking stations.
Does 21C Museum Hotel Louisville have on-site dining options?
The hotel features an on-site restaurant called Proof on Main that offers unique southern cuisine.
What are the check-in and check-out times at 21C Museum Hotel Louisville?
Check-in is at 16:00 and check-out is by 11:00.
Is parking available at 21C Museum Hotel Louisville?
Valet parking is available for guests at the hotel.
What types of massages can guests receive at 21C Museum Hotel Louisville?
Guests can select deep tissue massages and sports massages among other options.
Does 21C Museum Hotel Louisville offer business services?
The hotel provides a business center and 17 meeting rooms for business needs.
Are there any children's amenities at 21C Museum Hotel Louisville?
The hotel offers cots for children and has family-friendly policies.
What type of fitness facilities are available at 21C Museum Hotel Louisville?
Guests can access a fitness center and wellness facilities, including yoga classes and fitness locker rooms.
How close is 21C Museum Hotel Louisville to downtown attractions?
The hotel is centrally located, within 0.5 km of several downtown attractions.

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21C Museum Hotel Louisville
700 West Main Street, Louisville, 40202
Booking.com
Travellers review
8.9
21C Museum Hotel Louisville
trip-advisor
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